Pilauco is a paleontological and archaeological site located in the city of Osorno in Southern Chile. The site contains both human made lithic artifacts and megafauna remains–including gomphotheres. All the horizons containing megafauna and evidence of human activity date to the late Pleistocene. The calibrated radiocarbon dates indicate there was human activity in the site between 16,400 and -12,800 cal years B.P.

The site is claimed to contain evidence for the Younger Dryas impact hypothesis. This evidence include sediment layers with charcoal and pollen assemblages both indicating major disturbances as well as rare metallic spherules, and a Pt. Au and Pd peak anomaly originating from claimed to be derivative of airbursts or impacts.

Most of the stone artifacts found in Pilauco are made of volcanic rock such as dacite, rhyodacite and rhyolite from the Puyehue-Cordón Caulle Volcanic Complex immediately east in the Andes. Yet these rocks were imported by humans to the site as nearby rivers have not transported it.