The Grotte Marcel Clouet is a prehistoric site located in the French commune of Cognac in the west of the Charente department, in the valley of the Antenne, a tributary of the Charente. It was named in honor of the Charente prehistorian Marcel Clouet.

The stratigraphy established by Claude Burnez has 8 layers that he attributes all to the Upper Paleolithic. The stratigraphy established by André Debenath does not include the disappeared upper layers and has 6 layers. Layer 1 consists of ancient cuttings, and layers 2 and 3 have delivered some tools of the Mousterian layer 4 is very rich in ancient fauna and the lithic industry of the Mousterian.